9324904119
About

What is ?

5x2ml
5x5ml
  • APOSAN® (Apomorphine injection) is India’s 1st indigenously manufactured and marketed brand for the treatment of symptoms of Parkinson’s disease (PD)11
  • APOSAN® (Apomorphine injection) does not contain morphine and is non-addictive, and not a controlled substance
  • APOSAN® belongs to a class of medications called Dopamine agonists
  • APOSAN® is used to treat "OFF" episodes (Causes difficulty moving, walking, and speaking) in people with Parkinson's disease to get them to "ON"
  • Product Details
    I. Pack of 5 ampoule (2ml): Apomorphine hydrochloride injection 10mg/ml
    II. Pack of 5 ampoule (5ml): Apomorphine hydrochloride injection 10mg/ml
Indications

Treatment of motor fluctuations ("ON-OFF" Phenomena) in patients with Parkinson’s disease which are not sufficiently controlled by oral anti-Parkinson medications.

How it works How it works

How It Works?

  • APOSAN® contains Apomorphine hydrochloride salt and is non-ergoline Dopamine agonist with high selectivity for Dopamine D2, D3, D4 and D5 receptors
  • Due to stimulation of post-synaptic Dopamine D2-type receptors within the brain, Apomorphine shows improvement in motor and non-motor functions in Parkinson's disease
  • APOSAN® is Apomorphine hydrochloride that is used to treat the symptoms of Parkinson's disease. APOSAN® belongs to a group of medicines known as Dopamine agonists that stimulate nerve cells in the brain. These nerve cells then control movement and other body functions, to help reduce the symptoms of Parkinson’s

Advantages of

  • 4 to 10 minutes

    Starts working in
    4 to 10 minutes12

  • 60-90 minutes

    Effect of APOSAN® will last for
    60-90 minutes13

  • Improved quality of life

    Improved quality of life with APOSAN®

    Apomorphine is the most efficacious drug for therapy in treating the non-motor symptoms of PD (sleep problems, depression and anxiety, pain, urinary dysfunction etc)14

  • Reduction

    Reduction

    in 'off time' (both duration
    and severity of dyskinesia)15

  • Reduction

    Reduction

    Reported reduction
    in hallucination15

  • 85% reported

    85% reported improvement in night time sleep problems from insomnia and hypersomnia to Rapid Eye Movement (REM)15.

IS right for me?

APOSAN® can rapidly stop "OFF" episodes after it is administered. APOSAN® starts working as early as 4 to 10 minutes after being administered, most people feel relief from their "OFF" symptoms within 20 minutes. The Effect of APOSAN® lasts usually for 60-90 minutes. So it’s important that you continue to take your usual Parkinson’s Medications as directed by Doctor. Since APOSAN® bypasses stomach, you do not worry about your meal time. APOSAN® is reliable and just works at any time of the day.

Side Effects of APOSAN

References

11. SPC Apo-go Injections

12. MHRA PAR; APOMORPHINE 10 MG/ML SOLUTION FOR INJECTION, APOMORPHINE 10 MG/ML SOLUTION FOR INJECTION UKPAR TABLE OF CONTENTS http://www.mhra. gov.uk/home/groups/par/documents/websiteresources/con2033000.pdf

13. Pietz K., et al. Subcutaneous Apomorphine in late stage Parkinson’s disease: a long term follow up. J Neurol Neurosurg Psychiatry 1998; 65 :709–71.

14. Cell Physiol Biochem 2018;45:119-130.

15. M. Rosa-Grilo et al. / Parkinsonism and Related Disorders 33 (2016) S28eS35

Aposan has helped many more to get them On. We would love to hear your story.

Upload Now

Side Effects Of

It is important to involve a partner, close friend or relative who can give injections if you can’t move well enough to do it yourself.

  • Nausea, vomiting and hypotension Apomorphine can cause severe short-term nausea and sickness, so you may also be given an anti-sickness drug called Domperidone
  • Cardiac problems APOSAN® may affect your underlying heart problem
  • APOSAN® can cause your blood pressure to drop slightly. If you feel dizzy, you may need to check your blood pressure with your GP/Neurologist/Nurse
  • Sleeping problems APOSAN® can make some people feel sleepy or experience sudden onset of sleep
  • Injection sites can become sore and irritated Lumps (nodules) may appear under the skin where the needle is inserted. You can prevent them by making sure the place where the needle is inserted is clean, changing the injection site every day and gently rubbing your skin once you’ve taken the needle out
  • Some people experience an itchy or sore reaction at the injection site, but this is rare. If this does happen, speak to your neurologist/nurse
  • Hallucinations and delusions Speak to your GP, specialist or nurse about any hallucinations or delusions that you or the person you care for are experiencing
  • Impulsive and compulsive behaviour Some people who take Dopamine agonists, including Apomorphine, may experience impulsive and compulsive behaviour
x

Share Your Story

x